Between Lexington in the Shenandoah Valley and Richmond, I-64 uses a lower elevation crossing of the Blue Ridge Mountains located about 30 miles further north, where it runs parallel to U.S. Route 250 through Rockfish Gap. In contrast, through this section, the older US 60 is mostly a rural two-lane road. With the crossing of the Blue Ridge Mountains at White's Gap at a higher altitude in more rugged terrain, US 60 in this area offers much more challenging and weather-sensitive driving conditions, as well as a history of many crashes in the years before I-64 was completed.
East of north-south U.S. Route 29 (which runs parallel to the eastern slope of the Blue Ridge), the older US 60 and I-64 gradually converge as they pass through the rolling hills of the rocky Piedmont region in an easterly direction to reach the fall line at Richmond, where they again become very close.
From Richmond east to the harbor area near the mouth of Hampton Roads, US 60 again essentially parallels I-64 through Williamsburg and the Historic Triangle region, extending down the Virginia Peninsula east to the Hampton Roads Bridge-Tunnel. A few miles south of the bridge-tunnel, in Norfolk, US 60 diverges to follow the south shoreline of the Chesapeake Bay through Ocean View and past the south entrance to the Chesapeake Bay Bridge-Tunnel to reach Cape Henry. There it curves south to run along the Atlantic Ocean shoreline to end near the south end of the Virginia Beach resort strip.
In South Hampton Roads, the roads also separate. I-64 became part of the circumferential Hampton Roads Beltway and looping far south and west of Norfolk, rather than reaching the Atlantic Ocean. Although older, Route 60 continues its west to east travel, becoming the public roadway actually closest to the waters of the Chesapeake Bay and the Atlantic Ocean terminating near the traditional resort strip at Virginia Beach.
Although US 60 offers a bucolic interlude for many motorists in comparison with I-64, the western portion of the Lexington-Richmond section of US 60 can be very difficult to drive, especially for larger vehicles such as motor homes and commercial vehicles, or any vehicles during inclement weather. It was notorious for deadly crashes in the years before I-64 was completed.
Continuing east, there is an additional shorter section of mountainous terrain before the road levels out somewhat into the rolling Piedmont region through the middle belt of the state. At Sprouse's Corner, Sprouse's Corner in Buckingham County, north-south U.S. Route 15 is crossed. This is the last major intersection until reaching the outskirts of Richmond.
The road is two lanes for most of its journey eastward from Lexington, but widens to four lanes in Powhatan Virginia. Crossing into Chesterfield County, it intersects State Route 288, a semi-circumferential expressway around the southwestern quadrant of Metropolitan Richmond and becoming Midlothian Turnpike.
U.S. 60 in the Richmond area enters on Midlothian Turnpike. The road largely follows the path of the old Manchester Turnpike, built early in the 18th century. Nearby, remnants of the Chesterfield Railroad, first in Virginia can be seen just south of the current highway. Midlothian was the site of coal mines after about 1700, with product transported overland to Manchester which was Richmond's city city south of the river (until they merged in 1910). At Manchester, ships could dock in the navigable waters of the James River just east of the fall line.
U.S. Route 60 crosses the James River on the Manchester Bridge into downtown Richmond. Nearby in Richmond, it crosses U.S. Route 360, technically a spur. From Richmond, U.S. 360 extends southwest to Danville, Virginia just north of the North Carolina border and northeast to Reedville, Virginia on the Chesapeake Bay.
Rt. 60 leaves the Church Hill section of Richmond on Government Road and the Williamsburg Road, which follows the old Richmond-Williamsburg Stage Road for some distance in Henrico County. This area was the scene of several major American Civil War battles during the Peninsula Campaign in 1862, and the roadway borders federal cemeteries at Government Road near the city limits and at Seven Pines. There Nine Mile Road brings State Route 33 to the intersection.
East of Bottoms Bridge, in New Kent County and western James City County, US 60 is a lightly-traveled four-lane divided highway that is sometimes used as an alternate route to Interstate 64 when the latter becomes congested. Near Anderson Corner at the junction of Virginia State Route 30 (near I-64 at exit 227), US 60 swings somewhat south to pass through Toano and Norge to reach Williamsburg, which I-64 bypasses slightly to the north. (First designated through the area in the late 1920s, US 60 also has a shorter bypass of the Historic District which encompasses most Colonial Williamsburg attractions). At Williamsburg, the National Park Service's Colonial Parkway leads to both Jamestown and Yorktown.
At milepost 238 on I-64, Virginia State Route 143 begins. As Colonial Williamsburg opened, this four-laned route was built in the 1930s as Merrimack Trail to supplement US Route 60. It parallels both US 60 and I-64 all the way east through Williamsburg, James City, and York counties, and through Newport News to reach Fort Monroe (near the Hampton Roads Bridge-Tunnel) in Hampton.
East of Williamsburg, US 60 passes the multiple Anheuser Busch developments in James City County, which include an office park, the Kingsmill Resort, its Williamsburg brewery, and the Busch Gardens Europe theme park. East of there, US 60 narrows again to two lanes, passing through the historic Grove Community and past Carter's Grove Plantation in southeastern James City County.
Warwick Boulevard, once a major through traffic route, and now mostly a local connector road, is largely paralleled by newer highways, Interstate 64 and State Route 143 (Jefferson Avenue). These, with more lanes and higher speed limits, in combination with Warwick Boulevard, form the major east-west highways through modern-day Newport News.
The road was named for the former Warwick County, Virginia, one of the original eight shires of Virginia which consolidated with the City of Newport News in 1958 and assumed the better-known name. Warwick County was named in 1634 for Robert Rich (1587-1658), second Earl of Warwick and a prominent member of the Virginia Company of London, the proprietary venture which founded Jamestown in 1607. The western reaches of Warwick Boulevard transverse the Denbigh area, long the county seat of Warwick County.
Notable sites along Warwick Boulevard or close by, west to east, include:
Several miles east of Lee Hall, the road widens to four lanes near the entrance to Fort Eustis. From there, as Warwick Boulevard, US 60 stretches about 18 miles to reach downtown Newport News. Turning north, the roadway crosses into Hampton and passes through the downtown area to reach I-64, with which it shares the crossing of Hampton Roads to Norfolk via the Hampton Roads Bridge-Tunnel. (As a historical note, prior to 1957, when the bridge-tunnel was completed, the crossing was via a car ferry service. The bridge-tunnel was expanded to 4 lanes and tolls removed in the mid-1970s). In the early 21st century, Newport News was in the midst of a widening project to expand portions of Warwick Boulevard to six lanes. Another project in Newport News to relocate and widen the portion of Route 60 west of Fort Eustis and construct a new crossing of Skiffe's Creek is in a planning stage.
At East Ocean View, then roadway swings away from the bay front and becomes onto Shore Drive, passing the entrance to the Naval Amphibious Base Little Creek at Little Creek, Virginia as it heads east into the city of Virginia Beach. After passing the Navy Base, Shore Drive again runs close to the bay front and crosses US 13 near the southern terminus of the Chesapeake Bay Bridge-Tunnel. US 60 continues as a 4-lane divided highway as it crosses over Lynnhaven Inlet and towards the First Landing State Park and Fort Story at Cape Henry. At the end of the state park, the roadway briefly is called 83rd Street as it curves onto Atlantic Avenue, running parallel to the oceanfront from a few hundred feet to a block or so to the west passing through most of the most developed portion of the Oceanfront area of the resort city.
From Fort Story to the terminus, the routing of US 60 is geographically north-south although it is signed as an east-west route (except for one sign where Atlantic Avenue meets Pacific Avenue noting US 60 as a North-South route). When Atlantic Avenue meets Pacific Avenue, US 60 continues straight onto Pacific Avenue, through the entire resort strip, passing 22nd and 21st streets, which lead to and from the eastern terminous of both the former Virginia Beach-Norfolk Expressway (now I-264) respectively, continuing to meet the original Virginia Beach Boulevard at 17th Street. Near the southern end of Pacific Avenue, the eastern end of US 60 is just past the Rudee Inlet Bridge.