Trophoblasts become inert during pregnancy and are completely rejected by the fetus and mother at delivery. They can be seen as the thin membrane covering the fetus at birth, the caul.
|cytotrophoblast||inner layer||Single celled layer adjacent to trophoblast.|
|syncytiotrophoblast||outer layer||Thick layer that lacks cell boundaries and grows into the endometrial stroma. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.|
The first trimester human trophoblast cell line ACH-3P: A novel tool to study autocrine/ paracrine regulatory loops of human trophoblast subpopulations - TNF-[alpha] stimulates MMP15 expression.(Research article)
Dec 19, 2007; Authors: Ursula Hiden (corresponding author) ; Christian Wadsack (corresponding author) ; Nicole Prutsch ; Martin...