In medicine, a topical medication is applied to body surfaces such as the skin or mucous membranes, for example the vagina, throat, eyes and ears.

Some hydrophobic chemicals such as steroid hormones can be absorbed into the body after being applied to the skin in the form of a cream, gel or lotion. Transdermal patches have become a popular means of administering some drugs for birth control, hormone replacement therapy, and prevention of motion sickness. Chloramphenicol is an example of an antibiotic that may be used topically.

In dentistry, a topical medication may also mean one that is applied to the surface of teeth.

"Topical" is derived from the Ancient Greek topos (plural: topoi), "place" or "location".


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