Tiagabine

Tiagabine

Tiagabine () is an anti-convulsive medication produced by Cephalon and marketed under the brand name Gabitril. The drug was discovered at Novo Nordisk in Denmark in 1988. and was co-developed with Abbott. After a period of co-promotion, Cephalon licensed Tiagabine from Abbott/Novo and now are the exclusive producer. The medication is also used in the treatment of panic disorder as are a few other anticonvulsants.

Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, evidence is available that it operates as a selective GABA reuptake inhibitor.

Side effects

Tiagabine's most common side effects include confusion, difficulty speaking clearly/stuttering, mild sedation, and in doses over 8 mg, a tingling sensation (paresthesia) in the body's extremities, particularly the hands and fingers.

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