After signing with Bob Monaco, the promotion manager for Destination Music, their first hit single was "If I Needed Someone", which was not released in the US. It was soon followed by "Sugar and Spice," a Tony Hatch song that was a hit in 1964 for the English group The Searchers. The Shames' version reached #49 in the USA.
The group disbanded in December 1969, but reunited again and continues to tour. Jim "J.C. Hooke" Pilster is the only remaining orginial member of the current lineup. Two charter members of The Cryan' Shames have since passed away: bassist Dave Purple in June 2001 and his replacement Isaac Guillory on December 31, 2000.
| Year | Title | Chart positions | |
| Billboard Hot 100 | |||
| 1966 | "Sugar and Spice" | | |
| 1966 | "I Wanna Meet You" | | |
| 1967 | "It Could Be We're in Love" | | |
| 1968 | "Up on the Roof" | | |
| 1968 | "Young Birds Fly" | | |