Superior limbic keratoconjunctivitis is an ocular surface disease characterized by episodes of recurrent inflammation of the superior cornea and limbus, as well as of the superior tarsal and bulbar conjunctiva.
Even though the pathophysiology remains unclear, it is thought that mechanical trauma from tight upper lids or loose redundant conjunctiva could lead to the disruption of normal epithelium. This mechanical hypothesis is supported by the increased lid apposition of exophthalmic thyroid patients, who are known to have an increased incidence of superior limbic keratoconjunctivitis.
Patients present with red eye, burning, tearing, foreign body sensation, mild photophobia. Inflammation and thickening of the conjunctiva is observed, espedially at the limbus.
Lubrication is an effective treatment for this pathology.
Findings from Johnson & Johnson broaden understanding of superior limbic keratoconjunctivitis.(Clinical report)
Aug 17, 2010; Scientists discuss in 'In vivo evaluation of superior limbic keratoconjunctivitis using laser scanning confocal microscopy and...
Researchers from National Taiwan University describe findings in superior limbic keratoconjunctivitis therapy.
Apr 14, 2008; Data detailed in 'Conjunctival resection combined with tenon layer excision and the involvement of mast cells in superior limbic...