Serock has existed as a fortified Masovian settlement since at least 1065. It was granted city rights in 1417 and again in 1923.
Before World War II, there was a significant Jewish population in Serock. Today there are no Jews. In the summer of 2000, a visiting descendant of former residents, discovered that a number of gravestones (Matzevot) were piled up in the city park The stones had been gathered by a local non-Jewish resident who also roped off the area. In 2006, a visit by members of the Jewish Records Indexing-Poland project confirmed the situation and now an attempt is being made to restore or at least establish a memorial on the site of the former Jewish cemetery. The United States Commission for the Preservation of America's Heritage Abroad is involved under the guidance of The Honorable Lee R. Seeman.