The film is the first known dramatisation of one of the most notorious killing sprees in British history and was made to mark the fortieth anniversary of Hindley and Brady's trial. It was made with the full backing of the victims' families, and was based on two years research, including interviews with detectives, relatives of the murdered children, and Hindley's brother-in-law David Smith.
A Region 1 DVD release happened on April 29th, 2008. A Region 2 DVD release happened on July 7th, 2008.
On the evening of 6 October 1965, David Smith witnesses a horrific murder at Brady and Hindley's house; the victim is a 17-year-old boy, Edward Evans. After the murder, David is forced to help clean up the mess and stay at the house until the early hours of the morning. When he returns home and tells Maureen about the crime, she finds his story hard to believe. In the morning, however, the couple go to the police, and Brady is arrested. Brady admits to murdering Edward Evans but insists that David Smith was a willing accomplice.
Police recover a suitcase full of incriminating evidence from a locker at Manchester Central Station, and quickly suspect that Edward Evans may not have been their only victim. Smith is soon taken in by police for questioning, as both Brady and Hindley have tried to shift the blame upon him, but the police soon determine that Smith did not take part in any murders.
While questioning Brady and Hindley, the police read out the names of other missing children who have recently vanished in and around Manchester. To most of the names, Brady and Hindley respond "Never heard of him/her", with the exception of one: Pauline Reade, who had been Hindley's neighbour in Gorton. The evidence against the couple continues to mount; the most shocking comes in the form of pornographic photographs of a missing 10-year-old girl, Lesley Ann Downey, and a tape recording of the child's pleas for her life (these cries are not actually heard when the tape is played). Meanwhile, the police find the bodies of both Lesley Ann Downey and John Kilbride buried in shallow graves on Saddleworth Moor. David Smith is questioned about the murders and Hindley and Brady try to convince the police that he was also involved, but he is soon released after no evidence is found to implicate him.
On 21 April 1966, Brady and Hindley go on trial at Chester Crown Court, where they are greeted by a crowd of vigilantes. David Smith is the main prosecution witness, and Maureen, pregnant again, agrees to testify. During the trial, Lesley Ann Downey's mother, Ann West, and stepfather, Alan, barge into David and Maureen's apartment and attack them, believing that they were involved in Lesley Ann's murder. David and Maureen's unborn child is unharmed, while Mr. and Mrs. West are cautioned by the police.
Brady and Hindley are convicted of the murders of Edward Evans and Lesley Ann Downey. Brady is also convicted of the murder of John Kilbride, and Hindley is found guilty for being an accessory to the murder. Brady is sentenced to three concurrent terms of life imprisonment, while Hindley receives two life sentences and a seven-year fixed sentence.
The birth of their second child does nothing to alleviate public hostility towards David and Maureen. In fact, they find "Hindley Bitch" painted on their front door.
Five years later, Maureen lives alone in a different apartment while David has served a prison sentence for wounding a man who provoked him in a pub. David and Maureen have had two other children. Following some persuasion from her mother, Nellie, Maureen agrees to visit her sister, who has been locked up in Holloway Prison, while Brady (who the trial judge felt had influenced Hindley into committing murder) has been imprisoned elsewhere. When Maureen goes to Holloway, she comes face-to-face with a different Myra - a woman whose bleached-blonde hair has turned brown by this stage and who tells Maureen of the guilt she feels for the pain the she has inflicted upon the victims' families. By now having rediscovered her faith in Roman Catholicism, Myra tells Maureen that she has discovered her true self, that she's going to confess to the murders, and that she has severed all ties with Brady. Myra also tells Maureen about how their father used to beat her, and Maureen admits that he used to beat her, too. Myra gives Maureen some of Brady's photos, including one almost identical to the one taken on the grave of John Kilbride, and says that she never wants to see them again.
David isn't pleased when he learns that Maureen has been to see Myra, but Maureen argues that Myra has changed. David and Maureen then turn their thoughts to their children and agree to patch up their differences for the children's sake. In the last scene, Maureen leaves the house.
An epilogue follows, revealing the fates of Maureen, David, Ian Brady, and Myra Hindley.
The epilogue also reveals that it wasn't until 1986 that Brady and Hindley confessed to the murders of Pauline Reade and Keith Bennett. The two killers were taken back to Saddleworth Moor separately to help locate the bodies. Pauline Reade's body was eventually exhumed and buried in a proper grave, but Keith Bennett's body has yet to be found. The drama ends with a tribute to the victims.