After World War II, she was renamed the Santa Eliana. In 1960, she was lengthened and widened by the Maryland Shipbuilding and Drydock Company and converted into the first U.S.-flagged, all-container ship devoted to foreign trade, with a capacity of 382 containers below-deck plus 94 on-deck. She was renamed SS Sea in 1964, and SS Mayagüez in 1965.
Beginning in 1965, the Mayagüez sailed a regular route for Sea-Land Service, Inc in support of American forces in Southeast Asia: Hong Kong – Sattahip, Thailand – Singapore. On May 7, 1975, about a week after the fall of Saigon, Mayagüez left Hong Kong on what was said to be a routine voyage.
Duly retrieved from KR forces, the Mayagüez was taken out of service and eventually scrapped, in 1979.