While some findings may be classic, typical or highly suggestive in a certain condition, they may not occur uniquely in this condition and therefore may not directly imply a specific diagnosis. A pathognomonic finding on the other hand allows immediate diagnosing, since there are no other conditions in the differential diagnosis. A pathognomonic sign or symptom can sometimes be absent in a certain disease, since the term only implies that when it is present, the doctor instantly knows the patient's illness.
Singular pathognomonic signs are relatively uncommon. Examples of pathognomonic findings include Koplik's spots inside the mouth in measles, the palmar xanthomata seen on the hands of people suffering from hyperlipoproteinemia, or a tetrad of rash, arthralgia, abdominal pain and kidney disease in a child with Henoch-Schönlein purpura.
Pathognomonic signs
None or very few of the examples here are pathognomonic in the true sense of the word. For example, Parkinsonism is not only seen in Parkinson's disease.See also
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Last updated on Saturday October 04, 2008 at 08:34:47 PDT (GMT -0700)
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