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Paraneoplastic_cerebellar_degeneration
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Paraneoplastic cerebellar degeneration
Paraneoplastic cerebellar degeneration is a paraneoplastic phenomenon associated with lung, ovarian, breast, and other cancers.
It is believed to be due to an autoimmune reaction targeted against components of the central nervous system (specifically Purkinje cells and large brain stem nuclei). It is thought to be caused by an anti-neuronal Antibody known as anti-Yo.
It typically presents as a subacute progressive cerebellar ataxia, both truncal and appendicular.
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This article is licensed under the GNU Free Documentation License.
Last updated on Monday August 11, 2008 at 20:15:02 PDT (GMT -0700)
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This article is licensed under the GNU Free Documentation License.
Last updated on Monday August 11, 2008 at 20:15:02 PDT (GMT -0700)
View this article at Wikipedia.org - Edit this article at Wikipedia.org - Donate to the Wikimedia Foundation
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