The Old A.C.L. Union Depot (also known as the Palatka Railroad Station) is a historic Atlantic Coast Line Railroad depot in Palatka, Florida. It is located at 200 North Twelfth Street, and originally also served as a junction with Florida Southern Railway, Georgia Southern and Florida Railroad (SOU) and the Palatka Branch of the Florida East Coast Railway. On February 25, 1988, it was added to the U.S. National Register of Historic Places.
The station is used by Amtrak for both the Silver Service and the Sunset Limited, although the latter service has been suspended since Hurricane Katrina. It is also the location of the Palatka Railroad Preservation Society and the Browning Railroad Museum.