The sea expedition was transported by the ship Tonquin, under the command of Jonathan Thorn, an impatient and hard man. The Tonquin left New York on September 81810, and arrived at the Columbia River April 121811 to establish the first American-owned (if Canadian-staffed) outpost on the Pacific Coast, Fort Astoria (present-day Astoria, Oregon) which was near the Lewis and Clark 1805-1806 winter camp of Fort Clatsop at the mouth of the Columbia River. On the way to the Columbia the Tonquin stopped at Hawaii and picked up a number of Native Hawaiian laborers (called kanakas), including Naukane.
The Tonquin then sailed up the coast to trade where she was boarded by the Tla-o-qui-aht people of Clayoquot Sound, Vancouver Island, where 61 men were killed and the ship subsequently exploded by a surviving crew member.
The Overland Expedition of the Pacific Fur Company, often called the Astor Expedition or the Hunt Party, was led by Wilson Price Hunt. The party ascended the Missouri River as far as the Arikara Villages near present-day Mobridge, South Dakota, then west overland. They found hard times on the Snake River in southern Idaho, where they lost some goods and most of their food, and were forced to cache the rest of their trade goods and divided into fractions to make their way to the Columbia. Most members of the party reached Fort Astoria in January and February 1812.
After a number of set-backs, the Pacific Fur Company failed when the supply ship Beaver was late to arrive at Fort Astoria as anticipated. In addition the loss of the Tonquin left the post vulnerable. At risk of being captured by the British during the War of 1812, Fort Astoria and all other Pacific Fur Company assets in the Oregon Country were sold to the Montreal-based North West Company in October 1813.
In March, 1814 the North West Company's supply ship Isaac Todd arrived, along with a British warship with orders to destroy any American settlements. But then Fort Astoria was British and its employees under the protection of the North West Company. The Isaac Todd dropped off much needed supplies and offered some personnel, many of whom were former employees of the North West Company, comfortable passage back to Montreal and England. Alexander Henry and Donald McTavish, two veteran North West Company employees who had joined the Pacific Fur Company, drowned when their boat capsized in the Columbia River on the way to the Isaac Todd.