To pursue his interest in the entertainment industry, Jones formed his own production company, Homeboy's Productions and Advertising. He scored his first Hollywood job in 1987, writing for the NBC comedy A Different World, on which he had a small guest role in the season five finale. During 1991-92, Jones penned the FOX series Roc and, in 1993, he co-produced The Sinbad Show. He also made a brief appearance on the FOX sitcom Herman's Head in 1992.
Jones is a vegan.
Throughout Seasons One and Two of MADtv, Jones constantly produced funny characters like the Cabana Chat band leader Dexter St. Croix and Reverend LaMont Nixon Fatback, the vocal follower of Louis Farrakhan. He was also noted for his impressions of various people as Dennis Rodman, O.J. Simpson, Samuel L. Jackson, and Snoop Dogg.
The "O.J. Simpson Bloopers" sketch is arguably the most popular sketch featuring Jones. The sketch features parodies of his interviews doing mistakes such as being hit in the groin and wearing a wrong fitted glove by saying "It doesn't fit". Some scenes in the sketch were actual bloopers, especially any scene that has Artie Lange in it.
After two seasons on MADtv, Jones left the show at the end of its second season to pursue a movie career. However, Jones returned to MADtv in 2004 to celebrate its 200th episode. Jones appeared in the opening video "Hey MAD!" where he lampooned Andre 3000. With his guest appearance, Jones became the third (out of five) original cast member to return as a guest on the show. The other original cast members, who have returned, include: Nicole Sullivan, Phil LaMarr, Artie Lange and Debra Wilson.
During his time at MADtv, he roomed with Artie Lange, now a co-host on The Howard Stern Show. Orlando wouldn't allow Artie into the apartment if Artie had cocaine on his person. He was, however, according to Artie, very supportive and influential in helping to save Artie's life. Nicole Sullivan and David Herman of MADtv were also involved in the intervention (informing police and the show of his cocaine problem) of Artie Lange. This information was revealed on the June 12, 2006 episode of The Howard Stern Show on Sirius Satellite Radio by Artie Lange. Christa Miller, of The Drew Carey Show, was a roommate of Nicole Sullivan's at the time. Her appearance on The Howard Stern Show prompted Artie to reveal this information.
On July 28,2008, Steve Langford of Howard 100 News reported that during the taping of the MADTV famous Babe Watch skit, Orlando claimed that when he awoke one morning, there was a horrible stench in the room and Artie was missing. Orlando said the bed was loaded with excrement. When house keeping came to clean the room he grabbed his stuff and jumped out the window to avoid being blamed. Artie Lange did confirm the incident.
This exposure led to a plethora of opportunities for Jones. First, he hosted an HBO First Look special in 2000 and then, in 2003, Jones was given his own late night talk show on FX called The Orlando Jones Show. Although his talk show was short lived, Jones continued to make additional television appearances. In 2003, he appeared on the The Bernie Mac Show and on Girlfriends. In 2006, Jones decided to return to television as one of the lead characters of ABC's crime drama The Evidence, as Cayman Bishop. He also appeared in a seconds season episode of Everybody Hates Chris as Chris's substitute teacher.
During the 2000s, Jones' career began to branch out. In addition to his witty appearances in the 7-Up campaigns, Jones played the role of Clifford Franklin in The Replacements (2000) and he appeared in the comedy Chain of Fools (2000) and the horror film From Dusk Till Dawn 3: The Hangman's Daughter (2000). In 2001, Jones landed the role of Daryl Chase in the action-comedy Double Take (2001) alongside Eddie Griffin and worked with David Duchovny and Julianne Moore in Ivan Reitman's sci-fi comedy, Evolution (2001). Jones was also in the 2002 film Drumline alongside Nick Cannon and Zoë Saldaña and he appeared as the computer Vox in The Time Machine (2002). His other more recent films includes Biker Boyz (2003), Runaway Jury (2003) and House of D (2004). Jones recently had a cameo in the Chris Rock Film I Think I Love My Wife (2007).
Jones is one of eight original MADtv cast members to engage in some form of voice work after leaving the show. Only Bryan Callen has not appeared in voice acting projects. He appeared on the very first episode of Nick Cannon's Wild 'N Out.
|2009||Cirque du Freak||Alexander Ribs|
|I Think I Love My Wife||Wendell (Not Credited)|
|2006||Looking for Sunday||Einstein Steinberg|
|2004||House of D||Superfly|
|Biker Boyz||Soul Train|
|The Time Machine||Vox|
|2001||Evolution||Prof. Harry Phineas Block|
|Say It Isn't So||Dig McCaffrey|
|Double Take||Daryl Chase|
|2000||Bedazzled||Daniel/Dan/Danny, Esteban, Beach Jock, Lamar Garrett, Dr.|
|Chain of Fools||Miss Cocoa|
|The Replacements||Clifford Franklin|
|From Dusk Till Dawn 3: The Hangman's Daughter||Ezra Traylor|
|Liberty Heights||Little Melvin|
|Office Space||Steve, Magazine Salesman|
|New Jersey Turnpikes|
|1997||In Harm's Way||Andre|
|2008||New Amsterdam (TV series)||Harold Wilcox|
|2006||The Evidence (TV series)||Cayman Bishop|
|2003||The Bernie Mac Show||Party Planner|
|The Orlando Jones Show||Himself||Host|
|Girlfriends||Dr. Darren Lucas|
|2000||HBO First Look||Himself||Host|
|1995 - 1997||MADtv||Various Characters||Sketch Comedy|
|1994 - 1995||Sound fX||Himself||Host|
|1992||A Different World||Troy Douglas|
|Herman's Head||Other Woman|
|2006||The Adventures of Chico and Guapo||Chico, Guapo||Animated Comedy TV Series|
|2005||L.A. Rush||Ty Malix||Video Game|
|2004||Father of the Pride||Snack||TV Series|
|Halo 2||Marine Sergeant Banks||Video Game|
|1997||King of the Hill||Kidd Mookie||Animated Comedy TV Series|
|1993||Yuletide in the 'hood||TV Series|