As of late, with digital scanning and image manipulation, non-photo blue fulfills its function in a different way. The artist can do his sketch and inking in the traditional method and scan the page. Most scanners will detect the light blue lines. However, shifting to greyscale and increasing the contrast and brightness will cause the blue to disappear. Depending on the scanner and settings, this exact process may be different for each user, but the concept remains the same. The difference between the non-photo blue and black ink is vast enough that digital image manipulation can separate the two easily.
If one scans in a black and white bitmap setting, the exposure or threshold number can be set high enough to detect the black ink or dark images being scanned, but low enough leave out the non-photo blue. On a threshold scale of 0-255, this number would be approximately 140. Only with an extremely high threshold setting will the blue be detected. However, a setting this high would greatly distort the black lines and add a lot of noise and black speckles to the image, making it almost indistinguishable. Scanning in black and white makes it possible for the non-photo blue still to serve its original purpose, as notes and rough sketching lines can be placed throughout the image being scanned and remain undetected by the scan head.
There is no exact colour within the Pantone Matching System that matches non-photo blue.