Vaidišová has been playing tennis since she was six years old. She is a student of Nick Bollettieri and trains at the Nick Bollettieri Tennis Academy in Bradenton, Florida. Her serve is considered her biggest weapon. As of September 8, 2008, Vaidišová is ranked World No. 23. On August 9, 2006, at the age of 17 years, three months, and two weeks, she became the 12th-youngest player in WTA Tour history to be ranked in the top 10. She achieved a career-high ranking of World No. 7 on May 14, 2007.
Vaidišová is a face of Reebok and has been featured in their "I Am What I Am" and "Run Easy" campaigns. She also endorses Citizen Watch Co., Ltd and its Eco-Drive design. An avid reader, Vaidišová is part of the "Get Caught Reading Campaign" to encourage people to read more. She has taken part in other philanthropic causes, such as becoming an ambassador for PlayPumps International, a non-profit organization dedicated to bringing clean drinking water to African children. She is represented by Olivier van Lindonk of IMG.
Vaidišová finished the year as a top 100 player. As a qualifier at only her third WTA Tour main draw at inaugural Vancouver, Vaidišová became the sixth-youngest singles champion in tour history at an age of 15 years, three months, and 23 days. She also became the lowest-ranked player (World No. 180) and second qualifier (of three) to win a title in 2004. Vaidišová won her second title of the year at Tashkent, defeating Virginie Razzano in the final. On October 18, she made her top 100 debut at World No. 74, becoming the youngest player in the top 100 at the time.
Later in the year, Vaidišová reached the quarterfinals at the Japan Open Tennis Championships in Tokyo, defeating World No. 29 Tatiana Golovin in three sets en route for her career-best win, before losing to Klára Koukalová. Vaidišová made her Grand Slam debut at the US Open, losing to defending champion and World No. 1 Justine Henin, 6–1, 6–4, in the first round. She won ITF/Columbus, OH-USA at the start of the season and reached her then career-high No. 72 singles ranking on November 1.
Vaidišová finished the year with two WTA titles and a win-loss record of 31-8.
In early January, Vaidišová reached her first quarterfinal of the season in Hobart, by defeating Tatiana Perebiynis and Dinara Safina before losing to Iveta Benešová. Vaidišová picked up her first Grand Slam singles victory in her Australian Open debut, by reaching the third round with victories against Maria Vento-Kabchi and Jelena Kostanić. She subsequently fell to top seed Lindsay Davenport. Following the tournament, Vaidišová jumped in the rankings from World No. 70 to World No. 57.
In April, Vaidišová made her top 50 debut at World No. 47 and reached her first career Tier I quarterfinal at the Family Circle Cup in Charleston, South Carolina, saving two match points in a first round victory over qualifier Shahar Pe'er. She then posted her first top 10 victory over defending French Open champion Anastasia Myskina, before also defeating Shinobu Asagoe in three sets. Vaidišová then fell to Patty Schnyder in the quarterfinals, making her top 40 debut at World No. 34 on April 18.
In May, Vaidišová reached her first Tier III final in Istanbul, losing to top seed Venus Williams in the championship match. She made her debut at the French Open, defeating Lucie Šafářová in the first round before falling to 22nd-seeded Francesca Schiavone in the next round.
In August, Vaidišová reached the quarterfinals at Toronto, by defeating Shenay Perry, Nathalie Dechy, and Hana Sromova before losing to Justine Henin. Her ranking continued to improve, jumping from World No. 32 to World No. 27 on August 22.
In September, at the US Open, Vaidišová reached the fourth round for the first time at a Grand Slam event, by defeating Květa Peschke, Zheng Jie, and qualifier Ivana Lisjak before losing to Nadia Petrova.
Vaidišová's ranking improved following the US Open, going from World No. 28 to World No. 23 on September 12. She captured her first title of 2005 (and third of her career) in Seoul, defeating top seed Jelena Janković in the final without dropping a set during the week. She moved to World No. 21 at the start of October.
In that month, Vaidišová captured her second straight tour singles title in [[Japan Open Tennis Championships|Tokyo], winning when Tatiana Golovin retired, while trailing, 7–6(4), 3–2, due to left Achilles tendinitis in the final. On October 10, Vaidišová made her top 20 debut at World No. 18 and extended her winning streak to 15 matches, by winning her third consecutive tour singles title and fifth of her career; she beat Conchita Martinez and Gisela Dulko en route to the final, then overcame a 4–2 third-set deficit to defeat Nadia Petrova for the first time, 6–1, 6–7(5) 7–5, in the final.
With the Seoul, Tokyo, and Bangkok titles, Vaidišová became the first player since Lindsay Davenport in 2004 to win three titles in three weeks, and also became the sixth woman to win five Tour singles titles before her 17th birthday (after Tracy Austin, Andrea Jaeger, Monica Seles, Jennifer Capriati and Martina Hingis). On October 17, she improved her ranking from No. 18 to No. 17, another career-high.
In July, Vaidišová went 2–0 during the Czech Republic's 3–2 Fed Cup World Group Play-offs loss to France. She reached the semifinal on her debut in Stanford, losing, 7–5, 6–2, to Kim Clijsters. Vaidišová reached her career-first Tier I semifinal in San Diego, losing to Clijsters again. After her success in San Diego, Vaidišová moved from No. 12 to No. 9, her first career top 10 debut, becoming the 12th-youngest player in Tour history to crack the top 10, at an age of 17 years, three months and two weeks.
At the U.S. Open, Vaidišová made it to the third round, but lost to Jelena Janković, who later made it to the semifinal. In Beijing, she lost in the second round to Ai Sugiyama after a first round bye.
Vaidišová defeated Amelie Mauresmo for the second time at the Kremlin Cup in Moscow, after rallying from 1–6, 2–5 down and three match points, in their quarterfinal match. However, she lost to Nadia Petrova for a third time in their four meetings in the semifinal afterwards.
Vaidišová finished the year ranked #10, the first time she has ended the year in the top 10.
At the Australian Open in Melbourne, Vaidišová reached her second Grand Slam semifinal by defeating Jill Craybas, Milagros Sequera, Katarina Srebotnik, Elena Dementieva, and Lucie Safarova. She was beaten in the semifinal by the eventual champion, Serena Williams, 7–6, 6–4.
At the Tier II Open Gaz de France, Vaidišová was the fifth seed. She lost in round 16 to Lucie Šafářová, 6–4, 6–2. In March, she had a successful run at the Tier I event in Indian Wells, California, losing to Svetlana Kuznetsova in the quarterfinals 4–6, 6–3, 6–4.
In her first grass tournament of the season, the International Women's Open in Eastbourne, United Kingdom, Vaidišová lost in the quarterfinals to World No. 1 Justine Henin 6–2, 6–2. At Wimbledon, Vaidišová lost to Ana Ivanović in the quarterfinals 4–6, 6–2, 7–5, after failing to convert three match points. She had earlier dismissed the reigning champion and fourth seed Amelie Mauresmo in the fourth round.
Vaidišová was the out for two months after Wimbledon due to glandular fever and signed up for several tournaments before withdrawing. She returned at the US Open, where she lost to Shahar Pe'er in a third round match, 6–4, 3–6, 7–6(5).
Vaidišová's next event was the Kremlin Cup in Moscow, where she was the eighth-seeded player. She had defeated Russians Yaroslava Shvedova and Elena Vesnina in straight sets before losing to fourth-seeded Serena Williams in the quarterfinals 6–4, 7–6(7).
The next week in Zürich, Vaidišová reached the semifinals, by defeating Katarina Srebotnik, World No. 3 Jelena Janković, and Alyona Bondarenko all in straight sets. In semis, she faced world No. 1 Justine Henin, and despite coming back from 3–5 down in the third set, Vaidišová ended up losing, 3–6, 6–3, 7–5.
Vaidišová played three hard court tournaments in Australia to start the year. She lost to Li Na of China in the quarterfinals of the Tier III Mondial Australian Women's Hardcourts in Gold Coast. She then reached the semifinals of the Tier II Medibank International in Sydney, defeating Jelena Janković in the quarterfinals before losing to Svetlana Kuznetsova in the semifinals. At the Australian Open, Vaidišová won her first two matches in straight sets before defeating in the third round a 2000 Australian Open quarterfinalist, Ai Sugiyama. Defending champion Serena Williams then defeated Vaidišová in the fourth round 6–3, 6–4.
The week after the Australian Open, Vaidišová won both of her Fed Cup singles matches in the tie against Slovakia. At the Tier II Barclays Dubai Tennis Championships, Vaidišová lost in the second round to World No. 2 Ana Ivanović 6–4, 6–0.
The loss in Dubai was the first of six consecutive losses by Vaidišová, four of which were at Tier I tournaments and one of which was at a Grand Slam tournament. At the Tier I Pacific Life Open in Indian Wells, California, Vaidišová received a first round bye before losing in the second round to Australian Casey Dellacqua. At the Tier I Sony Ericsson Open in Key Biscayne, Florida, Vaidišová again received a first round bye before losing in the second round to qualifier Alisa Kleybanova of Russia. At the Tier I Qatar Telecom German Open, played on clay courts in Berlin, Vaidišová lost in the first round to Gisela Dulko of Argentina. At the Tier I Internazionali BNL d'Italia in Rome, Vaidišová lost in the first round to Ekaterina Makarova of Russia. Vaidišová then lost in the first round of the French Open to qualifier Iveta Benesova of the Czech Republic.
Vaidišová ended her losing streak at the Tier III DFS Classic, played on grass courts in Birmingham, United Kingdom. She won her first two matches before losing in the third round to World No. 81 U.S. player Bethanie Mattek. Vaidišová was the 18th seed at Wimbledon. She defeated World No. 8 Anna Chakvetadze of Russia in the fourth round 4–6, 7–6(0), 6–3 but then lost to unseeded World No. 133 Zheng Jie in the quarterfinals 6–2, 5–7, 6–1.
|Grand Slam (0)|
|WTA Championships (0)|
|Tier I (0)|
|Tier II (0)|
|Tier III (3)|
|Tier IV-V (3)|
|1.||August 15, 2004||Vancouver, Canada||Hard||Laura Granville||2–6, 6–4, 6-2*|
|2.||October 17, 2004||Tashkent, Uzbekistan||Hard||Virginie Razzano||5–7, 6–3, 6–2|
|3.||October 2, 2005||Seoul, Korea||Hard||Jelena Jankovic||7–5, 6–3|
|4.||October 9, 2005||Tokyo, Japan||Hard||Tatiana Golovin||7–6(4), 3–2 retired|
|5.||October 16, 2005||Bangkok, Thailand||Hard||Nadia Petrova||6–1, 6–7(5), 7–5|
|6.||27 May, 2006||Strasbourg, France||Clay||Peng Shuai||7–6(7), 6–3|
|No.||Date||Tournament||Surface||Opponent in the final||Score|
|1.||October 19 2003||Plzen, Czech Republic||Carpet Indoor||Andrea Hlavackova||7–6(5), 6–4|
|2.||February 22 2004||Columbus, U.S.||Hard Indoor||Peng Shuai||7-6(5), 7–5|
|Grand Slam Win-Loss||0–0||5–3||8–4||13–4||15–4||8–4||49–19|
|WTA Tour Championships||A||A||A||A||A||0–0|
|Doha||Not Tier I||A||0–0|
|Montréal / Toronto||A||A||QF||3R||A||1R||4–2|
|San Diego|| Not|
|Year End Ranking||None||77||15||10||'''12||N/A|