She is a former financial comptroller and municipal councillor in Arviat.
She was the Parliamentary Secretary to the Minister of Natural Resources in 2003. She has served as the chair and is currently the vice-chair of the Standing Committee on Aboriginal Affairs and Northern Development. She is also a member of the Liaison Committee, an associate member of both the Standing Committee on Canadian Heritage and the Standing Committee on Human Resources, Social Development and the Status of Persons with Disabilities. Karetak-Lindell retained her seat in the 2006 federal election, but later announced she will not be seeking re-election in the next federal election.