Former US Surgeon General, Dr. David Satcher assumed the role of interim president in addition to being the director of the National Center for Primary Care which is located at the Morehouse School of Medicine. Later he was honored as a full president.
On February 28, 2006 Morehouse School of Medicine (MSM) announced the appointment of John E. Maupin Jr., D.D.S. as the institution's next president. Dr. Maupin departed from his position of president at Meharry Medical College. In 2006 it admitted 53 students to its M.D. program making it the largest class since the school's inception.
| President | Tenure (years) |
|---|---|
| Louis W. Sullivan | 1981 – 1999 |
| James Gavin III | 2002 – 2004 |
| David Satcher | 2004 – 2006 |
| John Maupin | 2006 – Present |