Mitogen-activated protein kinase kinase

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Mitogen-activated protein kinase kinase (sic) is a kinase enzyme which phosphorylates mitogen-activated protein kinase. It is also known as MAP2K. It is classified as .

There are seven genes:

• (aka MEK1)
• (aka MEK2)
• (aka MKK3)
• (aka MKK4}
• (aka MKK5)
• (aka MKK6)
• (aka MKK7)

The activators of p38 (MKK3 and MKK4), JNK (MKK4), and ERK (MEK1 and MEK2) define independent MAP kinase signal transduction pathways.

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Last updated on Tuesday February 12, 2008 at 10:33:00 PST (GMT -0800)
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