Margaret of Dampierre (13 April 1350 – 16/21 March 1405) was Countess of Flanders (as Margaret III), Countess of Artois and Countess Palatine of Burgundy (as Margaret II) and twice Duchess consort of Burgundy. Through her mother, (Margaret of Brabant, daughter of John III, Duke of Brabant), the younger Margaret was also a heiress of the Duchies of Brabant and Limburg.
In 1357, the young Margaret, then seven, married Philip of Rouvres, grandson and heir of Eudes IV, Duke of Burgundy. Philip was eleven years old and her second cousin. He was count of Burgundy and Artois (1347–1361), Duke of Burgundy (1350–1361), and became yet Count of Auvergne and Boulogne (1360–1361).
Margaret was widowed in 1361, and with the death of her husband the duchy of Burgundy was inherited by John II of France (as John I of Burgundy). In 1363 Philip the Bold, John's youngest son, was granted the duchy as Philip II, and subsequently married its former duchess in 1369. Philip had earlier been Duke of Touraine (1359–1363), and became later also count of Charolais (1390–1404). When Margaret's father died in 1384, she and Philip inherited the counties of Artois, Burgundy, Flanders, Nevers, and Rethel. Philip died in 1404, and Margaret died the next year.
According to Guizot, her father had not wished her to marry a Frenchman, being more friendly to England; he was persuaded to agree to the marriage by his mother, Marguerite of France.