• Manifold, an abstract mathematical space which, in a close-up view, resembles the spaces described by Euclidean geometry.
• Manifold (general engineering) an arrangement of pipes used to redistribute the flow of a fluid or gas, typically from a single inlet to a number of outlets or vice versa
• Manifold (automotive engineering), an engine part which joins many connections into one, for example the exhaust manifold
• Hydraulic manifold, a component used to regulate fluid flow in a hydraulic system, thus controlling the transfer of power between actuators and pumps
• Manifold (scuba), in a scuba set, connects two or more diving cylinders, so that one diving regulator is fed by all the cylinders.
• Manifold chemistry, a piece of apparatus used in chemistry to manipulate gases. See Schlenk line and Vacuum manifold.
• Manifold (magazine) and 2mainfold (magazine) are magazines of the Warwick University mathematical community.
• River Manifold, a river in England
• The Manifold Way, a foot- and cyclepath which follows the old route of the Leek and Manifold Valley Light Railway
• John Manifold, an Australian poet and critic.
• Manifold System, a company that develops a popular, low-cost GIS software package
• The Manifold Trilogy by science fiction author Stephen Baxter.
• Manifold Records, a record label

See too:

• Manifold Destiny (about circumstances surrounding Grigori Perelman's proof of the Poincaré conjecture)
• Manifold Destiny (cookbook)