| Cause | Number of deaths resulting |
|---|---|
| Smoking | 435,000 deaths or 18.1% of the total deaths |
| Overweight and Obesity | 365,000 deaths or 15.2% of the total deaths. |
| Alcohol consumption | 85,000 deaths or 3.5% of the total deaths. |
| Infections | 75,000 deaths or 3.1% of the total deaths. |
| Toxic agents | 55,000 deaths or 2.3% of the total deaths. |
| Motor vehicle collisions | 43,000 deaths or 1.8% of the total deaths. |
| Incidents involving firearms | 29,000 deaths or 1.2% of the total. |
| Sexually transmitted infections | 20,000 deaths or 0.8% of the total. |
| Illicit use of drugs | 17,000 deaths or 0.7% of the total deaths. |