The Dead River connects Lake Eustis and Lake Harris. The only roadway to cross the river is U.S. Highway 441 near Dead River's southern mouth toward Lake Eustis. There are currently two businesses directly on the river: the former Dead River Vic's, now known as Nate's River Deck restaurant and a small fueling station and general store (The Dead River Marina).
For a historical look at Lake County waters, this was written in the 1930's "amid the slopes and waters of beautiful Lake County, are Leesburg, Eustis, Tavares, and Mount Dora, all possessed of excellent tourist accommodations and such natural and man-made beauty, combined with all sorts of sport advantages, that the sport-loving visitor is thrilled.
Bass fishing surpasses anything you have ever known in that line. Citrus fruits and other products abound. Golf courses are found in every community. As an all-year resort section, this is hard to equal."
Source: Excerpt from "Florida: The March of Progress" published circa 1930s by the Florida Department of Agriculture, Bureau of Immigration.