It was in New York's Washington Square Park that a mutual friend introduced her to Dmitry Brill, a Ukrainian expatriate and amateur D.J. The two started dating, and moved in together in an apartment in Williamsburg, Brooklyn from 1984 to 1989. During that time, the two with third member Towa Tei formed the band Deee-Lite and soon broke onto the world-wide music scene. Following almost 10 years of touring and performing, the band officially disbanded in 1994, following the end of Kirby and Brill's tumultuous romantic relationship.
Kirby had long been interested in art and design. Despite a lack of formal training, her artistic and design talents have been widely recognized, and she has lectured at several programs, including Princeton University and Cooper Union Art Institute. However, she is more well known for her writing skills, one of the major reasons behind the success of Deee-lite's music. Besides her lyrical works, her poetry has been included in such publications as the spoken word collection "Verbal Abuse."
Throughout her career, Kirby has been a vocal activist on the political front, specifically protesting against the Iraq War, social inequality and environmental issues. In addition, she has been very involved in the gay rights movement, which has garnered her a loyal following in the gay community.
The band's sound was a unique mix of house, techno and dance elements. Deee-Lite shot to stardom in 1990 with the release of the first album World Clique, and in particular with the smash hit "Groove is in the Heart". Kirby was very involved in the band's output: writing, producing, and performing the bulk of the band's songs. Kirby's sultry, feminine, and soulful voice backed up by the funky, catchy beats was truly unique for its time, and came to personify the club culture of New York City.
Known as much for their outrageous personae and costumes as for their music, the three took on larger-than-life alter-egos: Super DJ Dmitri, Jungle DJ Towa Tei, and Lady Miss Kier. Kirby is credited with designing and creating the look of the band, as well as much of the artwork accompanying the band's albums and marketing material. Her initial look relied on revamped and exaggerated retro '60s fashions, which was revolutionary at the time. Her signature look was a zip-up catsuit, platform shoes and flipped hair-do. At the height of the band's success, her style had a major influence on fashion trends, showing up in a variety of retail venues.
Deee-Lite followed their successful first album with a politically-charged second album, Infinity Within, in 1992. Their third album, Dewdrops in the Garden, was released in 1994 and saw a return to house roots with a new, more naturalistic tone. Neither of the two follow-up albums matched the commercial success of their debut. The second and third albums were hampered by difficulties with the label, which refused to promote, support touring, or fund contractual videos. The band functionally broke up during the writing of their third album in 1993, but Kirby and Brill decided to finish the project and tour together to promote the album before going their separate ways, and officially disbanding in 1994. In 1996, a remix album was released, and a greatest hits album was released in 2001.
She has since moved back to New York City, and is rumored to be putting together the long-anticipated solo album for release. Unreleased songs include "Me and my records", "Bulletproof", "Dance Police", "The Outer planets", "Black out love affair", "Wear U Out", "Go Down" and "Strip". Kirby occasionally releases snippets from her body of work on Myspace and her personal website. There are also several clips of her group and solo performances on YouTube. Most recently, Kirby has released a sound bite of "I Surrender" on Myspace.com, hinting that a solo album effort is still ongoing. On April 28, 2007 she performed at Coachella. She appears on the release from NYC noise band, Apollo Heights on a song titled "Winter In The Summertime", released in October 2007.