KXVO's schedule includes The CW, The CW4Kids and 4Kids (FOX) programs as well as reruns of The Simpsons, That '70s Show, Family Guy, Malcolm in the Middle, Smallville, Stargate SG-1, King of the Hill, and other shows. The station's DT-2 digital subchannel simulcasts KAZO-LP (Channel 57), which carries Pappas' independent Spanish language network TuVision.
With KXVO's original identity and tagline of "All Entertainment" in 1995, news did not seem like a natural fit. In the late 1990s and early 2000s, KXVO aired sixty-second "news updates" that promoted stories from that night's newscast on KPTM. These updates aired during the six-o-clock hour.
In 2001, KXVO station management made plans to produce a 5:30 pm newscast, utilizing on-air talent and production from sister station KPTM. After the terrorist attacks of September 11, 2001 and the resulting economic downturn, these plans were put on hold and eventually abandoned.
In the days following the 9/11 attacks, KXVO aired continuous news coverage from CNN Headline News.
Early in 2006, the station began airing a ten o'clock newscast, "The KXVO 15 10 O'Clock News," which was produced by KPTM. The show debuted on January 28, 2006. In April of the same year former MTV VJ and reality show host Brian McFayden was hired to anchor the program. McFayden left the show to explore other options in his career, amid rumors that he was becoming more and more difficult to work with. In any case, his hiring was unable to save the newscast's low ratings.
In late August 2006, comedian and Second City Training Center alumnus Matt Geiler was named the new anchor of "The KXVO 15 10 O'Clock News." By this time, the show had become some sort of sketch comedy program, with news content being handled by KPTM staff. Throughout its run, the show never registered a single ratings point, and was canceled in 2007.