Juan, Prince of Asturias

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Infante don Juan de Trastamara de Aragon y de Trastamara de Castilla, (28 June 1478 in Seville–4 October 1497), Prince of Asturias and heir of Spain, was the only son of Isabella I of Castile and Ferdinand II of Aragon who survived to adulthood.

At the age of 18 Juan married Margaret of Austria (1480-1530) in the Cathedral of Burgos in April, 1497. Six months later, on the way to the wedding of his older sister in Portugal, he died in Salamanca, possibly from tuberculosis. His wife was left pregnant and later gave birth to a stillborn child. Juan's death led to the inheritance of the Spanish kingdoms by the Habsburgs, after his sister married Philip the Handsome.

In 1492, Columbus named the newly discovered island of Cuba Isla Juana in deference to Prince Juan, at that time the heir apparent.

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