On a 1967 episode of Get Smart, Byner played a KAOS agent who made a phone call to the Chief of CONTROL (played by Edward Platt), performed a perfect impression of President Lyndon B. Johnson, and told the Chief he was fired and replaced with agent Maxwell Smart (Don Adams). Smart, the Chief and Agent 99 (Barbara Feldon) foiled this plot to undermine CONTROL, and Byner's character was arrested.
In 1970, he hosted about 25 episodes of a syndicated half-hour musical variety series called Something Else. He then hosted his own show in 1972 called the "John Byner Comedy Hour", where the character Super Dave was first introduced. In the late 1970s, he had a featured role as Detective Donahue on the tv series Soap. In the 1980s he hosted the Canadian TV comedy series, Bizarre. That show re-introduced many people to hapless daredevil Super Dave Osborne, played by Bob Einstein. Over the years he has done straight acting work and also light characters in otherwise serious dramas, such as the mostly-harmless con artist "Cotton Dunn" in the 1990s cop series Silk Stalkings.
One voice of his own invention is a high-pitched, raspy voice that defies easy description. It is vaguely similar to Donald Duck, only more intelligible. He has sometimes given that voice a character to go with it, "Felix Fossididdi". It was actually a voice that he and his brother came up with, which they would sometimes use when ordering in restaurants in order to try to spook the waitress. He used the voice for the character Gurgi in the Disney animated feature film The Black Cauldron.
In 2008, he stars in RoboDoc.
"The Pink Panther Laugh and a Half Hour and a Half Show" (1976) TV Series (voice) .... The Ant/The Aardvark