It was listed on the National Register of Historic Places in 1976.
The barracks have served as headquarters of the Louisiana National Guard. Prior to Hurricane Katrina in 2005, the Barracks complex had an extensive military museum in the old powder magazine and in a new annex, with a large collection of military items from every American war. The 2000 NRA Shooting Sports Camp and Coaches School was held at Jackson Barracks June 28 – July 2, 2000
In 2005, most Federal disaster response resources in Greater New Orleans were staged here prior to Hurricane Katrina. As the failure of the Federal levees made this area one of the most severely flooded during the effects of Hurricane Katrina in New Orleans, much equipment was lost and many personnel had to struggle with saving their own lives.
As of 2008, demolition of some severely damaged buildings and rebuiling of others is ongoing.