itching

Stimulation of nerve endings in the skin, usually incited by histamine, that evokes a desire to scratch. It is often transient and easily relieved. Pathological itching with skin changes usually signals dermatologic disease. Generalized itching without skin changes can occur in systemic diseases (e.g., metabolic and endocrine conditions, cancer, drug reactions, and kidney, blood, and liver diseases). Dry skin often itches. Treatment depends on cause.

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