A hemoprotein (also haemoprotein), or heme protein, is a metalloprotein containing a heme prosthetic group, either covalently or noncovalently bound to the protein itself. The iron in the heme is capable of undergoing oxidation and reduction (usually to +2 and +3, though stabilized ferryl [Fe⁺⁴] compounds are well known in the peroxidases).

Roles

Hemoproteins have diverse biological functions including:

• oxygen transport
• hemoglobin
• hemocyanin
• myoglobin
• neuroglobin
• cytoglobin
• leghemoglobin
• catalysis
• peroxidases
• cytochrome c oxidase
• ligninases
• active membrane transport
• cytochromes
• electron transfer
• cytochrome c
• catalase
• Sensory
• FixL (Oxygen sensor)
• sGC (Nitric Oxide sensor)
• CooA (CO sensor)

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