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Haplogroup L3 (mtDNA)
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In human genetics, Haplogroup L3 is a human mitochondrial DNA (mtDNA) haplogroup.

L3 is believed to have arisen between 84,000 to 104,000 years ago.

It is most common in East Africa, in contrast to sub-Saharan Africa where the haplogroups L1 and L2 represent two thirds of mtDNAs.

L3 is also sub-divided into several clades, one of which is believed to have spawned the macro-haplogroups M and N from which most non-Africans are descended.

One of these lineages, defined by loss of the DdeI site at np 10394, represents only a few percent of the African mtDNAs but appears to be the progenitor of roughly half of all European, Asian and Native American mtDNAs.

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