In 1992 Chambers formed his own band ' The Lemon Trees ' and wrote, produced and performed with them until they disbanded in 1995. Though the band only released one album, a second one was completed but not released because the record company didn't like it. Following the end of The Lemon Trees, Chambers spent time writing successfully with Cathy Dennis, Bryan Adams and others until an opportune meeting with Robbie Williams in January 1997
After recording for Williams' fifth solo album “Escapology” mid-2002, Chambers and Williams acrimoniously split amidst demands from Robbie Williams's management that Chambers stop writing for other artists. It was also alleged in Williams's book Feel that Chambers was demanding a ludicrously high Producer royalty hike, leading to the split. Chambers revealed in a 2005 interview that he and Williams were on speaking terms again and hinted at possible future collaborations. Chambers has claimed their songwriting partnership was 50.50, he wrote most of the music, while Williams' wrote the lyrics and some of the melodies. Williams subsequently started working with former Duran Duran member Stephen Duffy for his 2005 album “Intensive Care”. Chambers was not involved.
They re-united mid 2007 and are currently in LA together working on Robbie's upcoming album.
He co-wrote and produced four songs for Kylie Minogue's 2000 album Light Years, including the single "Kids" (a duet with Williams), "Loveboat", "I'm So High" and the camp classic "Your Disco Needs You".
Chambers and American songwriter Kara DioGuardi co-wrote "Shine" for Hilary Duff's self-titled album, which charted at #2 in the Billboard 200 chart and reached over 1 million in sales. Other US album collaborations include Ryan Cabrera's Take It All Away, "2 Become 1" for Jewel's album 0304, and Diana Ross for whom Guy produced the track Goin’ Back for Life and Love.
"Lemon Love", the debut album from Aslyn was produced by Chambers and Eric Valentine. 2004 saw the release of Brian McFadden's debut solo album “Irish Son” which Chambers heavily contributed to. First single “Real to Me” went straight in at #1 in the UK.
Other album releases that year included Natasha Bedingfield's debut album Unwritten, Delta Goodrem's second album Mistaken Identity and Beverley Knight's Affirmation. Chambers and Beverley wrote 4 tracks for the album including the single "Come as You Are". Beverley also performed her own accapella version of the Robbie Williams track "Angels" at 2005's Live 8 at Murrayfield, Edinburgh where Chambers was Musical Director.
The Isis Project, a French language album written with lyricist Keren Ann and vocalist Sophie Hunter is Chambers's own personal project, written as an 18th birthday present for his daughter Isis while she was four at the time. The track "L’onde Amere" also features on Keren Ann's latest album Nolita, released by Sleeper Music in 2005.
Charlotte Church's debut album Tissues and Issues features 3 co-written tracks: "Confessional Song", "Let's Be Alone" and "Casualty Of Love". Chambers collaborated with Jamie Cullum's for album Catching Tales on two tracks, "London Skies" and "Oh God".
Guy Chambers collaborated with Enrique Iglesias to write the ballad "First Day Of My Life". It was translated into Italian and recorded by Andrea Bocelli as the lead single from his first pop album. The English version of the song was recorded by Melanie C and became a smash #1 hit throughout Europe. Chambers collaborated with Iglesias for many other songs but none have yet been recorded.
He also worked with Tina Turner. There may be an album of new material in 2008.
Recently, Chambers worked with Darren Hayes to co-write "Who Would Have Thought?", a track that will be released on Hayes' forthcoming album This Delicate Thing We've Made, released on 23 August 2007. This song was released on Darren Hayes's Myspace, prior to the album release on 9 April 2007 along with an associated animation clip for the song.'
Chambers worked with the soul singer Kelis for a new album due out 2008
Most recent coöperation is with Eros Ramazzotti on his latest greatest hits album which includes 4 new songs. The song 'Ci parliamo da grandi' is written by Eros and Guy. The album "e2: energy" released on 31-10-2007 under the Sony-BMG label
Chambers and Cathy Dennis have been writing for a new solo record due out 2008
Chambers collaborated with Cathy Dennis on Kylie's new album 2 Hearts, which includes the track 'Sensitized'
Robbie Williams was included on the Radio 1 40 years album, with a cover of The Kinks 'Lola', produced by Chambers
Guy has been working with Island Def Jam artist Kerli, Mercury US signing Jessie James, and the American singer/ songwriter Anastacia.