• Grey matter, a major component of the central nervous system
• Gray Matter, an American hardcore punk band active in the 1980s and 90s
• Gray Matters, a new American record label
• Grey Matter, a British software retailer
• Gray Matter Interactive, an American computer game developer
• "Grey Matter", the opening track from the Oingo Boingo album Nothing to Fear.In fiction
• Gray Matter (short story), a horror story by Stephen King
• Gray Matters, a 2007 American romcom film starring Heather Graham
• Gray Matter, the fifth episode of the American TV series, Breaking Bad
• Gray Matter, a mystery adventure computer game by Jane Jensen, to be released in 2009
• Grey Matter, a member of race featured in the American animated TV series Ben 10

See also

• Greymatter