There is some disagreement among scholars as to which ethnic element predominated at Gnyozdovo. Although a Varangian presence is pronounced, nineteen mounds out of twenty contain ordinary burials of Krivich and Baltic men and women. The burial rite is mostly cremation. The most numerous finds are household utensils and pottery. As a general observation, the Gnyozdovo tumuli have parallels with the "druzhina kurgans" of Chernigov, such as the Black Grave.
Seven hoards of Byzantine and Arabian coins and a Byzantine dish bearing an image of Simargl have shown that the local community carried on a prosperous trade along the Dnieper. The metal objects represented include hauberks (not typical for Scandinavian sites), helmets, battle-axes, Carolingian swords, and arrows. Among the more surprising discoveries were an early folding razor with a copper handle and a pivoted scissors, probably the earliest found in Eastern Europe.
The most unexpected discovery at Gnyozdovo was a Kerch amphora with the earliest inscription attested in the Old Russian language. The excavator has inferred that the word горушна (gorušna), inscribed on the pot in Cyrillic letters, designates mustard that was kept there. This explanation has not been universally accepted and the inscription seems to be open to different interpretations. The dating of the inscription to the mid-10th century suggests a hitherto unsuspected popularity of the Cyrillic script in pre-Christian Rus.
Gnyozdovo is situated downstream from the Dvina–Dnieper portages, at a point where the Svinets and several small waterways empty into the Dnieper. Like Smolensk at a later period, Gnyozdovo flourished through trade along the Dnieper going south to Constantinople and north over portages to the Dvina and the Lovat, two rivers flowing to the Baltic Sea. At the time of its establishment, the local citadel served a defensive function against possible attacks on the portages, where the Norse traders would be at their most vulnerable. After internal tensions within Kievan Rus settled down, the site of Gnyozdovo "formed the critical exchange centre and refitting base on the route from the Baltic to the Black Sea".
The settlement declined in the early years of the 11th century, simultaneously with other Varangian trade stations in Eastern Europe. By the end of the century, Gnyozdovo's importance as a trade centre had been completely supplanted by nearby Smolensk.
According to one point of view, Gnyozdovo was the functional and economic predecessor of modern Smolensk. Soviet archaeologists established that the earliest settlement on the site of Smolensk goes back to the early 11th century. In other words, the emergence of Smolensk coincides with the decline of Gnyozdovo. The regional centre could have been moved from Gnyozdovo to Smolensk at some point following the Christianisation of Rus by Vladimir the Great.
Another school of thought is represented by Petrukhin and Pushkina who maintain that Smolensk and Gnyozdovo peacefully coexisted throughout the 10th century. According to this version, Gnyozdovo was a pogost of the ruling Kievan monarch which he used to levy tribute from the Krivichs. Since the knyaz's druzhina was composed primarily of the Norsemen, a substantial Varangian presence at Gnyozdovo seems to be well motivated. Concurrently, Smolensk was an urban centre of the Slavic (Krivich) population, where the regional veche was held. After Vladimir the Great established a local principality for his son, the administrative centre of the region and the seat of princely power was moved from Gnyozdovo to Smyadyn Castle near Smolensk.
The dichotomy of a Slavic veche centre and a Varangian druzhina station has parallels in other areas of Rus: compare Novgorod and Holmsgard, Chernigov and Shestovitsa, Rostov and Sarskoye Gorodishche, Yaroslavl and Timeryovo. In later centuries, the ruling princes from the House of Rurik preferred to settle in a fortified castle at a distance from their capital: in Vyshgorod rather than Kiev, in Smyadyn rather than Smolensk, in Kideksha rather than Suzdal, in Bogolyubovo rather than Vladimir.
Vasmer and other etymologists derive the name of Smolensk from the Smolnya River. If so, the original Slavic name for Gnyozdovo must have been different. Tatiana Jackson theorizes that it may have been derived from the name of the Svinets River, reconstructing it as Svinechsk (Свинеческъ). As the name of the river seems to be related to the Russian word for "swine" and ancient Gnyozdovo was situated on a promontory, Jackson identified this settlement with Sýrnes ("swine promontory" in Old Norse), one of seven or eight cities of Gardariki listed in the Norse geographical treatise of Hauksbók.