Any of a major class of proteins insoluble in pure water and soluble in dilute saline (salt) solutions. In their natural state, the protein chain is folded into a globular form. Globulins are found in many plants, especially cereals. Globulins in animal fluids include enzymes, antibodies (the gamma globulins), lipoproteins, complement components, transport proteins, and various types of fibrous and contractile proteins.
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Subgroup of the globulins. In humans and many other mammals, most antibodies are in the gamma globulin fraction of blood. A human gamma globulin preparation may be administered (by injection) to persons lacking immunity, either generally or to a particular disease, after exposure or before expected exposure.
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It is sometimes used synonymously with globular protein. However, albumin is also a globular protein, but not a globulin. All other serum globular proteins are globulins.
Protein electrophoresis is used to categorize globulins into the following four categories:
Serum globulins contribute to the discrepancies observed between the bromocresol green and bromocresol purple assays of serum albumin concentration
Jul 01, 2011; ABSTRACT The bromocresol green (BCG) and bromocresol purple (BCP) assays often yield discordant serum albumin results. This study...
Subcellular localization of soybean 7S globulin in HepG2 cells and LDL receptor up-regulation by its [alpha]' constituent subunit1
Jul 01, 2003; Manuscript received 10 December 2002. Initial review completed 7 February 2003. Revision accepted 18 March 2003. ABSTRACT The...