In over twenty-five works of fiction and poetry, Sorrentino explored the comic and formal possibilities of language and literature. His insistence on the primacy of language and his forays into metafiction mark him as a postmodernist, but he is also known for his ear for American speech and his attention to the particularities of place, especially of his native Brooklyn.
Sorrentino was born in Brooklyn, New York in 1929. In 1956, Sorrentino founded the literary magazine Neon with friends from Brooklyn College, including childhood friend Hubert Selby Jr. He edited Neon from 1956 to 1960, then served as editor for Kulchur from 1961 to 1963. After working closely with Selby on the manuscript of Last Exit to Brooklyn (1964). Sorrentino was an editor at Grove Press from 1965 to 1970, where one of his editorial projects was The Autobiography of Malcolm X.
He eventually took up positions at Sarah Lawrence College, Columbia University, the University of Scranton and the New School for Social Research in New York before being hired as a professor of English at Stanford University, where he served from 1982 to 1999.
His students included the novelists Jeffrey Eugenides and Nicole Krauss. His son, Christopher Sorrentino, is the author of the novels Sound on Sound and Trance.
The latter novel, a humorous postmodern romp, riffs on the metafictional possibilities introduced in Flann O'Brien's novel At Swim-Two-Birds, and is one of Sorrentino's most popular works.