Examples of GIRKs include a subset of potassium channels in the heart which when activated by parasympathetic signals such as acetylcholine through M2 muscarinic receptors, causes an outward current of potassium which slows down the heart rate. These are called muscarinic potassium channels (IKACh) and are heterotetramers comprised of two GIRK1 and two GIRK4 subunits.
Researchers from Tongji University report details of new studies and findings in the area of long QT syndrome.
Jul 10, 2010; Investigators publish new data in the report 'Identification of a Kir3.4 mutation in congenital long QT syndrome.' According to a...