In 1401,Brunelleschi entered a competition to design a new set of bronze doors for the baptistery in Florence. Along with another young goldsmith, Lorenzo Ghiberti, he produced a gilded bronze panel, depicting the Sacrifice of Isaac. His entry made reference to a classical statue, known as the 'thorn puller', whilst Ghiberti used a naked torso for his figure of Isaac. In 1403, Ghiberti was announced the victor, largely because of his superior technical skill: his panel showed a more sophisticated knowledge of bronze-casting; it was completed in one single piece. Brunelleschi's piece, by contrast, was comprised of numerous pieces bolted to the back plate. Ghiberti went on to complete a second set of bronze doors for the baptistery, whose beauty Michelangelo extolled a hundred years later, saying "surely these must be the "Gates of Paradise.
There is little biographical information about Brunelleschi's life to explain his transition from goldsmith to builder and, no less importantly, from his training in the gothic or medieval manner to the new classicism in architecture and urbanism that we now loosely call the Renaissance and of which Brunelleschi is considered the seminal figure. By 1400 there emerged an interest in ‘humanitas’ which contrasted with the formalism of the medieval period. But initially this new interest in Roman antiquity was restricted to a few scholars, writers and philosophers; at first it did not influence the visual arts. Apparently it was in this period (1402-4) that Brunelleschi and his friend Donatello visited Rome to study the ancient Roman ruins. Donatello, like Brunelleschi, had received his training in a goldsmith's workshop, and had then worked in Ghiberti's studio. Although in previous decades the writers and philosophers had discussed the glories of ancient Rome, it seems that until Brunelleschi and Donatello made their journey, no-one had studied the physical fabric of these ruins in any great detail. They gained inspiration too from ancient Roman authors, especially Vitruvius whose De Architectura provided an intellectual framework for the standing structures still visible.
Soon other commissions came, the most important of which were the designs for the dome of the Cathedral of Florence (1419-1436) and the Sagrestia Vecchia, or Old Sacristy of S. Lorenzo (1421-1440). The complex history of Santa Maria del Fiore need not be recounted except to state that by 1418 all that was left to finish was the dome. The problem was that when the building was designed in the previous century, no one had any idea about how such a dome was to be built, given that it was to be even larger than the Pantheon's dome in Rome and that no dome of that size had been built since antiquity. Because buttresses were forbidden by the city fathers, and clearly was impossible to obtain rafters for scaffolding long and strong enough (and in sufficient quantity) for the task, it was unclear how a dome of that size could be built, or just avoid collapse. It must be considered also that the stresses of compression were not clearly understood at the time, and the mortars used in the periods would only set after several days, keeping the strain on the scaffolding for a very long time. In 1419, the Arte della Lana, the wool merchant’s guild, held a competition to solve the problem. The two main competitors were Ghiberti and Brunelleschi, with Brunelleschi winning and receiving the commission. Brunelleschi was granted the 1st modern patent for his invention of a river transport vessel.
The dome, the lantern (built: 1436-ca.1450) and the exedrae (built: 1439-1445) would occupy most of Brunelleschi’s life. Brunelleschi's success can be attributed to no small degree to his technical and mathematical genius. Thus he invented a new hoisting machine for raising the masonry needed for the dome, a task no doubt inspired by republication of the seminal work De Architectura by Vitruvius, which describes Roman machines used in the first century AD to build large structures such as the Pantheon and the Baths of Diocletian, structures still standing which he would have seen for himself. He also issued one of the first patents for the hoist in an attempt to prevent theft of his ideas.
Of the two churches that Brunelleschi designed, the Basilica di San Lorenzo di Firenze, (1419-1480s) and Santo Spirito di Firenze, (1441-1481), both of which are considered landmarks in Renaissance architecture, the latter is seen as conforming most closely to his ideas. Brunelleschi used more than 4 million bricks in the construction of the dome.
Besides accomplishments in architecture, Brunelleschi is also credited with inventing one-point linear perspective which revolutionized painting and allowed for naturalistic styles to develop as the Renaissance digressed from the stylized figures of medieval art. In addition, he was somewhat involved in urban planning: he strategically positioned several of his buildings in relation to the nearby squares and streets for "maximum visibility". For example, demolitions in front of San Lorenzo were approved in 1433 in order to create a piazza facing the church. At Santo Spirito, he suggested that the façade be turned either towards the Arno so travelers would see it, or to the north, to face a large, prospective piazza.
The principal buildings and works designed by Brunelleschi or which included his involvement:
Brunelleschi's body lies in the crypt of the Florence Cathedral.