Eusebius may refer to:
- Eusebius of Alexandria (6th century), Christian author
- Eusebius of Angers (died 1081), bishop of Angers
- Eusebius of Caesarea (260-341), bishop of Caesarea Maritima, famous church historian
- Saint Eusebius of Cremona (died c. 423)
- Eusebius of Dorylaeum (5th century), bishop of Dorylaeum, opponent of Nestorianism and Monophysistism
- Eusebius of Emesa (300–360), bishop of Emesa
- Saint Eusebius of Fano (died c. 526)
- Eusebius of Laodicea (died c. 268), bishop of Laodicea
- Eusebius of Myndus (4th century), Neoplatonist philosopher
- Eusebius of Nicomedia (d. 341), bishop of Berytus, Nicomedia and Constantinople, leader of Arianism
- Saint Eusebius of Rome (died c. 357), a priest and martyr
- Saint Eusebius of Samosata (died c. 380), bishop of Samosata
- Saint Eusebius of Vercelli (283-381), bishop of Vercelli, opponent of Arianism
- Pope Eusebius (died after 310), Pope in 309 or 310
- Hwaetberht (d. 740s), Abbot of Monkwearmouth-Jarrow Priory, who wrote under the pen-name of Eusebius
Eusebius is also the name of:
- Jerome (340-420), Christian scholar and church father, whose full name was Eusebius Sophronius Hieronymus
- Karl Eusebius of Liechtenstein (1611–1684), the second prince of Liechtenstein