Entrepôts were especially relevant in the Middle Ages and in the early modern period, when mercantile shipping flourished between Europe and its colonial empires in the Americas and Asia. For example, demand for spices in Europe, coupled with the long trade routes necessary for their delivery, led to a much higher market price than the original buying price. However, traders often did not want to travel the whole route, and thus used the entrepôts on the way to sell on their goods. However, this also led to even more attractive profits for those who persevered to travel the entire route.