The village of Netherpool gradually changed its name to the 'Port of Ellesmere', and by the early 19th century, to Ellesmere Port. Settlements had existed in the area since the writing of the Domesday Book (the suburbs of Great Sutton, Little Sutton and Hooton are all mentioned). Many of the village names are derived from Old Norse, in common with much of the rest of the Wirral Peninsula, which had been an extensive Viking settlement. The first houses in Ellesmere Port itself, however, grew up around the docks and the first main street was Dock Street, which now houses the National Waterways Museum. Station Road, which connected the docks with the village of Whitby, also gradually developed and as more shops were needed, some of the houses became retail premises. As the expanding industrial areas growing up around the canal and its docks attracted more workers to the area, the town itself continued to expand.
By the mid-20th century, thanks to the opening of the Manchester Ship Canal in 1894 and the Stanlow Oil Refinery in the 1920s, the town had expanded so that it now incorporated the villages of Great and Little Sutton, Hooton, Whitby, Overpool and Rivacre as suburbs. The town centre itself had moved from the Station Road/Dock Street area (now part of the Westminster housing estate) to an area that had once been home to a stud farm (indeed, Ellesmere Port and Neston borough council officially refer to the town centre as 'Stud Farm' for housing allocation purposes) around the crossroads of Sutton Way/Stanney Lane and Whitby Road. Demand for housing was further increased with the opening of the Vauxhall Motors car plant in 1962. Between the 1950s and 1980s, a number of new housing estates were developed, many of them on the sites of former farms such as Hope Farm and Grange Farm. Most of these estates consisted of both council housing and privately-owned homes and flats. In the mid-1980s, the Port Arcades, a covered shopping mall was built in the town centre, which complemented the erection of Lewis's store which was bought out by Asda prior to the completion of the Port Arcades. By the 1990s, it was the retail sector rather than the industrial that was attracting workers and their families to the town. This was boosted with the building of the Cheshire Oaks outlet village and the Coliseum shopping park, which also included a multiplex cinema; prior to this, following the demolition of the King's Cinema in Little Sutton, the town's only cinema had been a single screen in the EPIC Leisure Centre.
The town continues to grow and expand, and more housing estates and shops are being built. The industrial sector is still a major employer in the town although in recent years, a number of factories have been closed and jobs lost.
The Vauxhall plant at Ellesmere Port is now Vauxhall's only factory in Britain since the closure of the Luton plant in 2004, and currently produces the Astra and Vectra models for the British market. Doubts over the plant's future were ended in 2007 when General Motors confirmed that the next generation Astra will be built at the plant when it is launched in 2010 . The Vectra's replacement is also expected to be built at the plant from 2008.
Ellesmere Port is part of the Ellesmere Port and Neston parliament constituency. The current MP is Andrew Miller (Labour).
In 2007, plans were announced which proposed combining the borough of Ellesmere Port and Neston with the Chester and Vale Royal districts to form a new "West Cheshire" unitary authority. On 25 July 2007, following a consultation period, the name of the new unitary authority was officially announced to be City of Chester and West Cheshire.
Ellesmere Port railway station has frequent electric trains to Liverpool via the Wirral Line of the Merseyrail network. There is also an infrequent service to Helsby, with the route passing through Stanlow and Elton.
The Manchester Ship Canal joins the Mersey estuary north-west of Ellesmere Port at Eastham, but the town is also the northern terminus of the Shropshire Union Canal (which used to exchange goods with sea-going boats at what is now the National Waterways Museum).