She graduated from New York University School of Law in 1919 and was admitted to the bar in Indiana and New York.
On April 6 1921, Elizabeth Harrison married James Blaine Walker (January 20 1889 - January 15 1978), a grandnephew of Secretary of State, James G. Blaine, a member of her father's cabinet.
Their daughter, Jane Harrison Walker, married Newell Garfield, a grandson of Interior Secretary James Rudolph Garfield, and great-grandson of President James Garfield. Elizabeth Harrison was founder and publisher of "Cues on the News", an investment newsletter for women.