Biology

• Extracellular matrix, any material part of a tissue that is not part of a cell

Science

• Electro chemical machining, a method of working hard materials
• Electron Cloud Model, an atomic model
• Electronically commutated motor, an electric motor which uses electronic switching to drive the motor rotation
• Electronic countermeasures, a part of electronic warfare
• Electronic control module, a unit to control electrical systems

Math

• Elliptic curve method, an algorithm for integer factorization

Management information system / Business

• Electronic contract manufacturing, a term related to the outsourcing of electronic assembly
• Enterprise Content Management, a strategy in the information technology industry

Business

• Equity Capital Markets, a financial term
• Error Correction Mechanism, a type of econometric model, closely linked with the concept of cointegration
• Explora Capital Management, an investment company

Organizations

• Every Child Ministries, a Christian charity for African children
• European Common Market, the common market of the European Community
• European Congress of Mathematics
• ECM (record label), a record label
• Electret microphone, a type of condenser microphone
• Engine Control Module, Car parts related
• Entitlement Control Message, a message carrying conditional access information in a digital broadcast conditional access system
• Error correction mode, a fax protocol
• Exceptional case marking verbs, a linguistic term