He is the older brother of Donovan Raiola, who is on the practice squad for the St. Louis Rams.
In his first year, he became the first freshman offensive lineman to start a game for the Cornhuskers since Rob Zatechka in 1991. In 1999, he became the first sophomore center for the team since Dave Rimington to participate in postseason play setting a school record for knockdowns which he bettered in 2000. He was widely picked as an All-American in 2000.
In 2002, Raiola started for all 16 games of the season, winning the Chuck Hughes Most Improved Player award. He was a key member of the offensive line which allowed only 20 quarterback sacks for the season, the lowest for the NFL in that season and then a franchise record. Raiola protected both quarterback Joey Harrington and running back James Stewart.
Raiola was again a key part of the offensive line in 2003, starting in all 16 games again. During that season, the offensive line allowed just 11 sacks, a new record for the franchise. He also played more special teams, becoming the long snapper when Bradford Banta broke his clavicle against the San Diego Chargers.
In 2004, Raiola started at center in all 16 games. The Lions' offensive line helped the team's rushing attack to be ranked second for the seven last games of the season. He again became responsible for long snapping after Jody Littleton incurred a hamstring injury against the Washington Redskins in the middle of November. His reliability and strong performance led to the Lions offering him a five-year contract extension in March 2005.