Jones exhibited artistic promise at an early age, even entering his drawings into exhibitions of children's artwork. He wrote that from the age of six he knew that he would devote his life to art. At fourteen, he persuaded his parents to allow him to abandon traditional education for art school, and in 1909, he entered the Camberwell Art School, where he was introduced to the work of the Impressionists and Pre-Raphaelites.
With the outbreak of the First World War, Jones enlisted with the Royal Welch Fusiliers and served on the Western Front until the end of the war. His experiences in the trenches were to prove extremely important in his later painting and poetry, especially his involvement in the fight at Mametz Wood.
He died in Harrow, Middlesex in 1974. His grave can be found in Crofton Park, Lewisham, SE13, near Brockley.
Eric Gill split with the Guild of SS. Joseph and Dominic and moved with his family and some followers to Capel-y-ffin, a village in southern Wales, to pursue a rural way of life. Jones spent much of the years 1924 to 1927 living with the Gills and assorted hangers-on in a rambling former monastery just outside Capel-y-ffin. He had already become engaged to Gill's middle daughter, Petra, whose characteristic long neck and high forehead continued as standard female features in Jones's artwork for the rest of his career, even though his engagement to her did not last more than a couple of years. Jones continued to visit his family home in Brockley until the mid 1930's and some of his sketches depict the house and garden.
Jones's major illustrated series include wood engravings produced for editions of The Book of Jonah, The Chester Play Of The Deluge, Aesop's Fables and Gulliver's Travels as well as for a Welsh translation of the Book of Ecclesiastes, Llyfr y Pregethwr. He produced an important group of copperplate engravings for an edition of The Rime of the Ancient Mariner. He also executed commissions for one-off engravings such as his illustration for T.S. Eliot's The Cultivation of Christmas Trees.
Despite his success and growing reputation as an illustrator, Jones seems to have become disaffected by the medium. He professed great disappointment in the way that his illustrations for Gulliver's Travels had been subsequently hand-coloured by art students, and complained about the reproduction of the very dark wood engravings for The Chester Play of The Deluge. This may have influenced his decision later in life to concentrate on painting. His style changed over time from more traditional watercolour landscapes to a unique mixture of pencil and watercolour resulting in dense and busy works full of symbolism. His best-known paintings include early seascapes such as "Manawydan's Glass Door" and later works on legendary subjects, such as Trystan ac Esyllt (Tristan and Iseult). He is also much admired for a genre that he devised later in life, which he termed "painted inscriptions", and these exert a continuing influence on calligraphers.
His next book, The Anathemata, appeared in 1952 (again published by Faber). Inspired in part by a visit to Palestine during which he was struck by the historic parallels between the British and Roman occupations of the region, the book draws on materials from early British history and mythology and the history and myths of the Mediterranean region to explore the possibility of small cultures resisting the power of empire. The poem received mixed reviews in the press, but was acclaimed by other literary artists such as W. H. Auden, Kathleen Raine and William Carlos Williams. Douglas Cleverdon produced dramatised readings of In Parenthesis and The Anathemata for the BBC Third Programme.
For the rest of his life, Jones worked on a long poem, of which The Anathemata was intended to form part. Sections of the incomplete work were published as individual poems, mainly in the London literary magazine Agenda, but in 1974, they were collected for publication in book form as The Sleeping Lord and Other Fragments (once again under Faber's auspices). A posthumous volume of previously-unseen materials was edited by Harman Grisewood and René Hague, and was published by Agenda Editions as The Roman Quarry.
On November 11th, 1985, Jones was among 16 Great War poets commemorated on a slate stone unveiled in Westminster Abbey's Poet's Corner. The inscription on the stone was written by a fellow Great War poet, Wilfred Owen. It reads: "My subject is War, and the pity of War. The Poetry is in the pity.
In 2002 the text of three short poems was published for the first time in Wedding Poems, edited by Thomas Dilworth. Two of these poems ("Prothalamion" and "Epithalamion", amounting to 271 lines) had been written while living in London during the Blitz, for the marriage of Harman and Margaret Grisewood. The third poem, "The Brenner" (24 lines), had been written on March 18, 1940 to mark the meeting of Mussolini and Hitler on the Brenner Pass. According to their editor, the publication of these poems brought into print "all the known completed poetry by David Jones".