The bank was founded by Rollin C. Dart and his son, Doc Campbell Dart, chief executive officer from 1943 to 1960. The founder's grandson, Rollin Dart, was chairman from 1962 to 2005, and president from 1962 to 1999. Under Rollin Dart, the bank expanded to serve nearby areas including Holt, Lansing, and Grand Ledge. Ronald Rhoades took over as president and chief executive officer in 1999, and since 2005 also serves as chairman.
In 1995, Dart National Bank participated in the financing of Oldsmobile Park, the city-owned stadium for the Lansing Lugnuts minor league baseball team.