Born on April 30 1951, Lucas was adopted when he was eight months old by a conservative Pennsylvania couple. His father was an FBI agent; his mother was a housewife. He graduated in 1969 from Conestoga High School in Berwyn, Pennsylvania. In the 1960s and 1970s, Lucas became interested in the political left and discovered an attraction towards men. He recalls that his coming out made it possible for him to develop as a playwright and as a person.
In 1973, Lucas left Boston University with a Bachelor of Arts in theatre and creative writing. His mentor, Anne Sexton, urged him to try his luck in New York City as a playwright. He worked in many day jobs while performing in Broadway musicals including Shenandoah, On the Twentieth Century, Rex, and Sweeney Todd.
Lucas met Norman René in 1979. Their first collaboration was Marry Me a Little in 1981. The two wrote a script incorporating songs that had been written for but discarded from Stephen Sondheim musicals, and René also directed. They followed this with the plays Missing Persons (1981) and Blue Window (1984); Three Postcards (1987), an original music by Lucas and Craig Carnelia; and another play, Reckless (1983). In 1990 they joined forces for what would prove to be their biggest commercial and critical success, Prelude to a Kiss. They also joined forces for the feature film Longtime Companion (1990), the 1992 film adaptation of Prelude with Alec Baldwin and Meg Ryan, and the 1995 film version of Reckless with Mia Farrow and Mary Louise Parker.
Following his early work on romantic comedies, Lucas began to write more serious works about AIDS, including The Singing Forest and The Dying Gaul, the latter of which was made into a film that Lucas also directed. Lucas also authored the book for the musical The Light in the Piazza, and directed the world premiere at the Intiman Theater in Seattle. The Lincoln Center production, directed by Bartlett Sher, garnered him a Tony Award nomination.
Lucas has also directed classic plays such as Loot. While some critics have divided his work into gay plays (Blue Window, Longtime Companion) and straight plays (Reckless, Three Postcards, Prelude to a Kiss), Lucas has always written about human problems in a universal manner. He directed Birds Of America, a film starring Matthew Perry and Hilary Swank, in 2007.
He has also received a Tony Award nomination (for the book of Light in the Piazza). Fellowships include those from the Guggenheim and Rockefeller Foundations, the National Endowment for the Arts, and the Pew Charitable Trusts. Perhaps most notably, he was nominated for the Pulitzer Prize for Drama for his plays Prelude to a Kiss and "The Dying Gaul".