Corticotropin-releasing hormone receptor

Corticotropin-releasing hormone receptor (CRHR) is a G protein-coupled receptor that binds corticotropin-releasing hormone (CRH). There are two forms of the receptor designated as type I and 2, each encoded by a separate gene (and respectively).


The CRHR is an important mediator in the stress response. Cells in the anterior lobe of the pituitary gland known as corticotropes express the receptor and will secrete adrenocorticotropic hormone (ACTH) when stimulated.


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