Corticotropin-releasing hormone receptor (CRHR) is a G protein-coupled receptor that binds corticotropin-releasing hormone (CRH). There are two forms of the receptor designated as type I and 2, each encoded by a separate gene (and respectively).
The CRHR is an important mediator in the stress
response. Cells in the anterior lobe
of the pituitary gland
known as corticotropes
express the receptor and will secrete adrenocorticotropic hormone (ACTH)