The school, which serves grades 9-12, is a part of the Clear Creek Independent School District. Clear Brook serves several communities, including portions of Friendswood, Houston, and unincorporated Harris County. The communities of Sterling Knoll, Bay Glen, Bay Knoll, Bay Pointe, Northfork, Heritage Park, Autumn Creek, Wedgewood, Pipers Meadow, Forest Bend, and Sageglen are served by the school.
Clear Brook also has five assistant principals who are in charge of five different smaller learning communties: Mr. Steven Kees, School of Public Service and Communications; Mr. Tim Rogers, School Visual and Performing Arts; Mrs. Nina Zoch, School of Business and Applications; Mr. Sven Schultz, School of Engineering and Industrial Design; and Mrs. Jennifer Gault, School of Medical and Health Sciences.
The school fight song is "The Victors", the same fight song as the University of Michigan. Clear Brook High School also shares the same mascot as U of M: the wolverine. The school mascot is named Big Will.
The school celebrated its first Texas state championship title in 1990, won by the girls' waterpolo team.
Notable school alumni include:
The inspiration for the school's mascot as well as the school's colors was the movie Red Dawn, which was popular among high school students at the time of the school's inception.
The following intermediate schools feed into Clear Brook High School: Brookside, Clear Lake, and Westbrook.