In New York, a premiere of Chrétien's new process impressed the major Hollywood film studios of the time, who were eager to win back lost audiences from television’s allure. 
Twentieth Century Fox bought the rights of the Anamorphoscope. (Predecessor company Fox Film Corporation had experimented with another widescreen process, Fox Grandeur, in 1929-1931.) However, the format needed more development before it would be ready to use. The first of Chrétien's lenses were quickly transported to Hollywood where they were further analyzed. From this analysis the basis of CinemaScope was formed.
Twentieth Century Fox's pre-production of The Robe was halted so that the film could be changed to CinemaScope, what Fox president Spyros Skouras called the future of filmmaking. Fox's famous advertising slogan "Movies are Better than Ever" gained credibility with the ground breaking 1953 film The Robe. With the introduction of CinemaScope, the movie industry was able to re-assert its distinction from its new competitor — television.
The comedy How To Marry A Millionaire was the first film to be shot in CinemaScope. However, The Robe was released first. Fox utilized its influential people to promote CinemaScope. With the success of The Robe and How To Marry A Millionaire, the process became a hot property in Hollywood. Fox licensed the process to many of the major film studios including Columbia, Warner Bros., Universal, MGM and Walt Disney Productions.
The Walt Disney Company was one of the first companies to license the CinemaScope process from Fox, and among the features and shorts they filmed with it, created one of the best-regarded examples of early CinemaScope productions with the live-action epic 20,000 Leagues Under the Sea. 
Due to initial uncertainty a number of films were shot simultaneously with anamorphic and regular lenses. Despite early success with the process, Fox did not stick to their claim of shooting every production with the process. CinemaScope as a trade name was reserved for "A" productions, while "B" productions in black and white commenced in 1956 at Fox under the trade name, "RegalScope."
In April 1953, a technique simply now known as "wide-screen" appeared and was soon adopted as a standard by all "flat" film productions in the US. In this process, a fully exposed 1.37:1 Academy ratio-area is cropped in the projector to a wide-screen aspect ratio by the use of an aperture plate, also known as a soft matte.
Aware of Fox's upcoming CinemaScope productions, Paramount introduced this technique in March's release of Shane with the 1.66:1 aspect ratio, although the film was not shot with this ratio originally in mind. Universal-International followed suit in May with a 1.85:1 aspect ratio for Thunder Bay. By summer of 1953, Paramount, Universal, MGM, Columbia, and even Fox's B-unit contractors, under the banner of "Panoramic Productions" had switched from filming flat shows in a 1.37:1 format, and used variable flat wide-screen aspect ratios in their filming.
The fundamental technique that CinemaScope was built on was not patentable because the anamorphoscope had been known for centuries. Anamorphosis had been used in visual media such as Hans Holbein's painting, The Ambassadors (1533), as early as the sixteenth century. Some studios sought to develop their own systems rather than pay Fox.
In response to the demands for a higher fidelity spherical widescreen process, Paramount created an optical process, VistaVision, which shot horizontally on the 35 mm film reel, and then printed down to standard 4-perf vertical 35 mm. Thus, a finer grained negative was introduced, and consequently less grainy prints. The first Paramount release in VistaVision was White Christmas. VistaVision died out in the late 1950s, with the introduction of finer grained film stocks.
RKO used the Superscope process in which the standard 35 mm image was cropped and then optically squeezed in post-production to create an anamorphic image on film.
Another process called Techniscope was developed by Technicolor Inc. in the early 1960s, using normal 35 mm cameras modified for two perforations per frame instead of the regular four and later converted into an anamorphic print. Techniscope was mostly used in Europe, especially with lower budget films.
Many European countries and studios used the standard anamorphic process for their wide-screen films, identical in technical specifications to CinemaScope, and renamed to avoid the copyrights of Fox. Some of these include Euroscope, Franscope, and Naturama (the latter used by Republic Pictures). In 1952-53 Warner Brothers also planned to develop an identical anamorphic process called Warnerscope, but after the premiere of CinemaScope, Warners decided to license it from Fox instead.
A general problem with expanding the image meant that there could be visible graininess and brightness problems. To combat this, larger formats were developed (initially a too-costly 55 mm for Carousel and The King and I) - and then abandoned (both films were eventually reduction printed at 35 mm, although the aspect ratio was kept at 2.55:1). Later Fox re-released The King and I in the 65/70 mm format. The initial problems with grain and brightness were eventually reduced thanks to improvements in film stock and lenses.
CinemaScope lenses were detrimented by barrel distortion when the anamorphic power was decreased, and objects approached close to the camera. Close-up shots would slightly over-stretch an actor's face, and telephoto shots would appear as if they were being rolled over a bump in the middle of the picture. This problem was avoided at first by composing wider shots, but as anamorphic technology lost its novelty, directors and cinematographers sought compositional freedom from these limitations. Issues with the lenses made it difficult to photograph animation using the CinemaScope process. Nevertheless, many animated short films and a few features were filmed in CinemaScope during the 1950s, including Walt Disney's Lady and the Tramp (1955).
The 1988 John Waters film Hairspray uses the trademark as a crack on the weight of an overweight teenage girl who wants to star on a TV dance show: "please; this show's not being filmed in CinemaScope!". A 2002 Broadway musical version of Hairspray and a 2007 film adaptation of the Broadway show retain this joke as part of the lyrics of one of the show's songs, "(The Legend of)" Miss Baltimore Crabs".